March 9, 2021

FDA Approves New Acetaminophen Injection Dose

The FDA recently approved a new acetaminophen injection for the management of mild to moderate pain, and for the management of severe pain with adjunctive opioid analgesics.

While oral acetaminophen has been available for decades, intravenous (IV) formulations are relatively new and have previously only been available in 1000mg doses. This new approval includes a 1000mg and 500mg dose.

According to the drug label, this injection may be given as a single or repeated dose, but only as a 15-minute IV infusion. Like any form of acetaminophen, long-term use of this drug can cause liver toxicity. Patients already at risk of liver disease should not receive acetaminophen.

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