The FDA is warning that dental problems have been reported with medicines containing buprenorphine that are dissolved in the mouth. Dental problems, including tooth decay, cavities, oral infections, and loss of teeth, can be serious and have been reported even in patients with no history of dental issues. Buprenorphine is used to treat pain as well as to help individuals with opioid use disorder (OUD) reduce opioid use. A new warning for dental problems will be added to drug labels.
